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마이크로칩 검사
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​생체전자신호 검지용 피부인터페이스 전극설계

​(Skin-interfaced electrode for bioelectronics)

​We study skin-interfaced electrode designs for low-noise and high-reliability acquisition of bioelectrical signals. Based on ultrathin and conformal electrode structures, we minimize impedance instability and motion-induced noise at the skin–electrode interface and apply these designs to ECG monitoring and skin hydration (impedance) sensing.

  • Skin-interfaced electrode platforms for bioelectrical signal sensing

  • Hybrid electrode structures for robust signal acquisition under mechanical deformation

  • Motion artifact mitigation through conductive hydrogel-based interfacial buffering

  • Impedance-based skin hydration monitoring

바이오 소재 기반 바이오 전자소자​

​(Bioelectronic devices based on biomaterials)

​We study fully biomaterial-based biosemiconductor devices that enable adaptive charge transport and multifunctional bioelectronic operation.  Beyond environmental responsiveness, the biosemiconductor transistor demonstrates UV photodetection through light-induced charge de-trapping and functions as a synaptic device, emulating excitatory postsynaptic current (EPSC) behavior under electrical stimulation. This research establishes biosemiconductors as a versatile platform for adaptive sensing, optoelectronics, and neuromorphic bioelectronics.

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바이오 소재 리소그래피 및 나노패터닝 공정​

​(Nanopatterning and lithography for biomaterials)

​We study nanofabrication methods for biomaterials to enable the realization of biocompatible nanoscale electronic and photonic devices for advanced human-machine interfaces.

  • Silk-protein-based 2.5D gray-scale electron beam lithography

  • Photolithography of silk protein using deep ultraviolet (DUV)

  • Two-photon-lithography for 3D microscale photonics

  • Colloidal self-assembly-based 3D photonic crystal fabrication

​바이오포토닉스 나노광학구조

​(Nanoscale photonic structures for biophotonics)

​We study nanoscale photonic structures to enable high-precision light modulation at nanoscale dimensions, which can be applied to biosensing and photo-stimulation.

  • Protein-based nanoscale color filter

  • Photonic crystal & biocompatible laser

  • Plasmonic-resonator-based biosensors

  • Nanoscale optical vortex generator

마이크로니들 기반 전기/광학 생체 인터페이스

​(Electrical/Optical bio-interface by microneedles)

Conventional skin-mounted electrodes face limitations in reliably acquiring electrical signals from underlying tissue due to the presence of the stratum corneum. Our silk-based microneedle electrodes directly penetrate the skin and establish contact with biological tissue, thereby forming electrical interfaces with reduced influence from the skin barrier. At the microneedle–tissue interface, ionic signals within the tissue couple with electronic charges in the electrode, rise to an ionic–electronic interface. This enables low-impedance electrical access to tissue and allows for stable, spatially localized electrical signal acquisition.

       Optically, by engineering the tip geometry, localized optical responses can be induced without relying on the intrinsic optical properties of the material. Such structure-based optical responses are described by structural color, where the reflection and scattering characteristics of light vary depending on the tip architecture.

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고기능 경피약물전달 시스템 

​(Advanced transdermal drug delivery systems)

​A high-efficiency transdermal drug delivery platform designed to penetrate the skin barrier—the major obstacle in drug administration—  and deliver active ingredients deep into the skin.

  • Dual-layered electronic tattoos (e-tattoos) for stable drug loading and releasing through the hybrid patch composed of the conductive layer and the drug-loaded silk reservoir layer.

  • Skin treatment to create the optimal environment for active ingredients within the patch to penetrate deeper and faster through skin pretreatment.

  • Active permeation to enable effective passage of drugs through the skin barrier using electrical and thermal stimulation.

인체 & 식물 호흡 실시간 모니터링 

​(Real-time respiratory and transpiratory monitoring)

​The biosemiconductor-based e-tattoo enables non-invasive and long-term monitoring of respiration by directly detecting humidity variations generated during breathing.

  • Silk biosemiconductor e-tattoo:

    • The moisture-responsive e-tattoo utilizing humidity-dependent semiconducting behavior and skin-compatible adhesion.

  • Highly porous nanofiber architecture:

    • The highly porous nanofiber structure to provide the breathability and rapid moisture absorption/desorption, enabling fast and reliable electrical responses to subtle humidity changes.

  • Long-term respiration and transpiration monitoring

    • The e-tattoo to enable real-time discrimination of human respiratory states and long-term monitoring of plant transpiration by continuously transducing physiological moisture variations into stable electrical signals.

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Department of Biomedical Engineering

Department of Electronic Engineering

Hanyang University, Korea

© 2022 by Sunghwan Kim

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